これにより、副腎皮質からのコルチゾールの過剰分泌が引き起こされます。急性のコルチゾールのスパイクは脂肪分解性ですが、慢性の絶え間ないコルチゾールの上昇は、 内臓脂肪細胞のリポタンパク質リパーゼ（LPL） を上方制御する一方、末梢組織では下方制御します（Epel et al.、心身医学）。簡単に言うと、慢性コルチゾールは脂肪を四肢から腹腔に直接再分配します。
Aly Owen is a certified nutritionist specializing in metabolic health, intermittent fasting protocols, and sustainable weight loss with over 8 years of clinical experience. All guidance is verified against peer-reviewed literature.
📚 Scientific Studies & Medical References (5 Sources)▼
FastingTracker adheres to strict editorial standards, citing peer-reviewed clinical trials and authoritative medical institutions.
New England Journal of Medicine (2019): de Cabo R, Mattson MP. Effects of Intermittent Fasting on Health, Aging, and Disease. N Engl J Med. 381(26):2541-2551.
PubMed 31881139 • DOI
Cell Metabolism (2014): Levine ME, Suarez JA, Brandhorst S, et al. Low Protein Intake and Periodic Fasting Promote Longevity and Autophagy. Cell Metab. 19(3):407-417.
PubMed 24606898 • DOI
Obesity (Silver Spring, 2018): Anton SD, Moehl K, Donahoo WT, et al. Flipping the Metabolic Switch: Understanding and Applying Health Benefits of Fasting. Obesity. 26(2):254-268.
PubMed 29086496 • DOI
Annual Review of Nutrition (2017): Patterson RE, Sears DD. Metabolic Effects of Intermittent Fasting. Annu Rev Nutr. 37:371-393.
PubMed 28715993 • DOI
Autophagy (2010): Alirezaei M, Kemball CC, Flynn CT, et al. Short-term fasting induces profound neuronal and systemic autophagy. Autophagy. 6(6):702-710.
PubMed 20534972 • DOI
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